Fascination About indazole-3-carboxylic acid
Fascination About indazole-3-carboxylic acid
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indazole substitution sample, on the other hand, they call for harsh disorders or lengthy routes to the key intermediates restricting their software. Selective N
Oven-dried laboratory glassware was used for carrying out the many synthetic procedures. Melting points had been taken in open capillaries on Sisco melting place apparatus and so are offered uncorrected.
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Interestingly, the methoxy oxygen of 27a participated in hydrogen bond formation with Asp641, whereas the fluorine atoms formed hydrophobic interactions with Val492 and Ala640.
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